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A mother watched with dread as a nurse inserted a tube in her baby's head. Blood streamed into the anemic 4-month-old who already has malaria, the mosquito-borne disease that kills a million African children every year.
In a daring experiment in Europe, scientists used mosquitoes as flying needles to deliver a "vaccine" of live malaria parasites through their bites. The results were astounding: Everyone in the vaccine group acquired immunity to malaria; everyone in a non-vaccinated comparison group did not, and developed malaria when exposed to the parasites later.
A vaccine that may become the world's first to prevent malaria shows promise in protecting African children, researchers said Monday, calling the results a "major milestone."
Researchers trying to create the world's first malaria vaccine are launching a massive medical trial as early as next month involving 16,000 children that could be the largest such trial ever conducted on children in Africa.
Extreme Genetic Variability In Malaria Parasite FoundResearchers at the University of Maryland School of Medicine Center for Vaccine Development (CVD) have charted the extreme genetic differences that occur over time in the most dangerous malaria parasite in the world.
Trial debut for malaria vaccine from mosquito spitA unique malaria vaccine extracted from the saliva of infected mosquitoes this week received clearance from the US Food and Drug Administration to be tested in people.
Malaria Vaccine Hits TargetDrug researcher W. Ripley Ballou remembers the moment he realized that GlaxoSmithKline Plc's experimental malaria vaccine might save millions of lives.
You can get paid to catch malariaHow far would you go to help wipe out one of the world's worst scourges? Seattle-area residents will soon be able to go all the way: allowing themselves to be bitten by malaria-infected mosquitoes to aid in the quest for new vaccines and drugs.
Making a malaria vaccine à la Louis PasteurThe sign on the wall reads "Emergency Response Procedures for a Mosquito Release." Among them are "Do Not Leave the Room or Open Any Doors!!!" and "Do Not Panic!"
The more bites the better immunity Exposure to the saliva of biting insects could later protect people against infection by insect-borne parasites.
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