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The Wire

US and Canada regulators approve Pfizer-Wyeth deal

Pfizer Inc.'s $68 billion purchase of Wyeth will close Thursday after antitrust regulators in the U.S. and Canada cleared the deal, which will make Pfizer the world's largest drugmaker by revenue.

S&P removes Wyeth from indices before acquisition

In the latest sign that Pfizer Inc.'s $68 billion purchase of Wyeth will go through, Wyeth's stock has been removed from two key investor indices.

FDA requires Chantix, Zyban to have warning

The Food and Drug Administration will require two smoking-cessation drugs, Chantix and Zyban, to carry the agency's strongest safety warning over side effects including depression and suicidal thoughts.

Pfizer CEO got $14.8 million in 2008 compensation

Pfizer Inc.'s chief executive received a 2008 compensation package valued by The Associated Press at $14.79 million, up 17 percent from 2007, after a year when the drugmaker reorganized operations and set in motion a mega-acquistion.

Pfizer CEO: Wyeth merger will bring what's needed

Eager to dispel doubts about the difficulties of executing Pfizer Inc.'s $68 billion tie-up with Wyeth, Pfizer's CEO said it will be done more like microsurgery than just stitching two huge corporations together.

How the major market indexes fared

Investors worried about the recession have turned to a strategy of cherry-picking stocks — sending tech shares higher and industrials lower. The market's concerns Monday were focused on two fronts: the economic stimulus proposal now before the Senate, and a possible plan to give further aid to the nation's banks. Meanwhile, mostly negative economic data and news of more layoffs helped extend the gloomy mood that gave the market its worst January ever.

Pfizer deal gives Wyeth say on board, breakup fee

Drug giant Pfizer Inc.'s agreement to acquire rival Wyeth would give Wyeth directors a voice on Pfizer's board and includes hefty penalties aimed at preventing the deal from collapsing, according to a regulatory filing made Thursday.

Pfizer: US ruling maintains Lipitor patent term

The U.S. Patent & Trademark Office on Tuesday issued a notice allowing drugmaker Pfizer Inc. to correct a technical defect in one of the patents involving Pfizer's cholesterol medicine Lipitor, the world's top-selling drug.

Pfizer 3Q profit triples vs. weak year-ago results

Pfizer Inc.'s profit tripled in the third quarter, mainly because a huge charge depressed last year's results, despite flat sales. Its earnings narrowly beat Wall Street's earnings expectations.

Some Doctors Balk at Inhaled Insulin

Pfizer's stab at giving diabetics insulin without needles is getting more praise than prescriptions so far. Exubera, a powdered form inhaled through a special device, was introduced last year in a targeted launch to specialists, a debut analysts deemed disappointing. While doctors applaud Pfizer Inc.'s effort to find a new way to deliver insulin, some are concerned about the drug's long-term effects on the lungs, cost and insurance coverage.

The Vine
Tons of Industry Released Drugs Taint US Water: AP Report
Source: Yahoo! News

U.S. manufacturers, including major drugmakers, have legally released at least 271 million pounds of pharmaceuticals into waterways that often provide drinking water, contamination the federal government has consistently overlooked, according to an Associated Press investigation.

Drug Pitchmen: Actor, Doctor or Pfizer's Option
Source: The New York Times

Surely the best message we can derive from the Dr. Robert Jarvik episode is that it may be time to rethink the advertising of prescription drugs

Pfizer to End Lipitor Campaign by Jarvik
Source: The New York Times

The ads featuring Dr. Robert Jarvik, a pioneer in artificial hearts, created false impressions, the company said.

Betting an Estate on Inhaled Insulin
Source: The New York Times

Alfred E. Mann is betting nearly $1 billion of his own money that he can succeed where Pfizer failed.

Drug Ads Raise Questions for Heart Pioneer
Source: The New York Times

Dr. Robert Jarvik's appearance in television ads for Lipitor has helped rekindle a smoldering debate.

Drug Approved. Is Disease Real? Doctors deny existence of Fibromyalgia
Source: The New York Times

The first drug to treat fibromyalgia has been approved, but some dispute the very existence of the condition.

Drug Approved. Is Disease Real?
Source: The New York Times

The first drug to treat fibromyalgia has been approved, but some dispute the very existence of the condition.

F.D.A. Investigates Quit-Smoking Drug
Source: The New York Times

Government scientists are investigating whether a drug from Pfizer used to help smokers quit cigarettes also increases suicidal thoughts and violent behavior.

Maker of Lipitor Digs In to Fight Generic Rival
Source: The New York Times

Many patients on the cholesterol drug are switching to a cheaper alternative, but Pfizer is not letting its flagship product go down without a fight.

Pfizer's Birthplace, Soon Without Pfizer
Source: The New York Times

The drug giant will shut its plant on Flushing Avenue in Brooklyn, but still plans to help the neighborhood where the company began.

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